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Transcriptome guided metabolic network analysis reveals rearrangements of carbon flux distribution in <i>Neisseria gonorrhoeae</i> during neutrophil co-culture

2022-12-20

Abstract excerpt

The ability of bacterial pathogens to metabolically adapt to the environmental conditions of their hosts is critical to both colonization and invasive disease. Infection with Neisseria gonorrhoeae (the gonococcus, Gc) is characterized by the influx of neutrophils (PMNs), which fail to clear the bacteria and make antimicrobial products that can exacerbate tissue damage. The inability of the human host to clear Gc...

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Literature Corpus work
a4285da7-46f6-51ae-b02e-1aea76c7c2e0
DOI
10.1101/2022.12.19.521143
Open publication

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Transcriptome guided metabolic network analysis reveals rearrangements of carbon flux distribution in <i>Neisseria gonorrhoeae</i> during neutrophil co-cultureDOI 10.1101/2022.12.19.521143
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