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A capsular polysaccharide-expressing live vaccine suppresses streptococcal toxic shock-like syndrome and provides sequence type-independent protection during <i>Streptococcus suis</i> infection

2018-05-31

Abstract excerpt

Streptococcus suis ( S. suis ) is an encapsulated zoonotic pathogen, which is responsible for bacterial meningitis and streptococcal toxic shock-like syndrome (STSLS). Despite many attempts to develop an effective vaccine, none is currently available. Here, a capsular polysaccharide (CPS)-expressing attenuated mutant 2015033 was constructed by deleting five virulence-associated factors ( sly , scpA , ssnA , f...

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Literature Corpus work
a42804d2-28a7-5d2e-a932-b93456eee265
DOI
10.1101/335349
Open publication

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A capsular polysaccharide-expressing live vaccine suppresses streptococcal toxic shock-like syndrome and provides sequence type-independent protection during <i>Streptococcus suis</i> infectionDOI 10.1101/335349
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