Pathway-Centric Visualization of Cell-Cell Communication in Single-Cell Transcriptomics Data

Abstract excerpt

<h4>Objective</h4> Single-nuclei transcriptomics enables investigating ligand-receptor mediated cell-cell communication between different cell-types. However, current tools do not allow for non-programmatic means to access this analysis. Additionally, most methods can not account for molecular pathways involved in downstream receptor signaling in cell-cell communication. <h4>Methods</h4> We developed scVizComm,...

Topics

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• Acute Myeloid Leukemia Research
• Bioinformatics and Genomic Networks
• Cardiomyopathy and Myosin Studies
• Cardiovascular Effects of Exercise
• Single-cell and spatial transcriptomics
• Viral Infections and Immunology Research

Identifiers and source

Literature Corpus work

a40aaafa-c973-5cf4-86c6-db2c6dddc123

DOI

10.1101/2025.07.25.666732