Article
Genome-wide association study identifies five risk loci for pernicious anemia and implicates the role of HLA-DR15 haplotype
2020-10-14
Abstract excerpt
Pernicious anemia is a rare condition characterized by vitamin B12 deficiency anemia due to lack of intrinsic factor, often caused by autoimmune gastritis. Patients with pernicious anemia have a higher incidence of other autoimmune disorders, such as type 1 diabetes, vitiligo and autoimmune thyroid issues. Therefore, the disease has a clear autoimmune basis, although the genetic susceptibility factors have thus fa...
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Identifiers and source
- Literature Corpus work
- a3c97414-66ce-547e-8e9c-3ddf24384f6b
- DOI
- 10.1101/2020.10.13.20211912