Article

Untangling Covid-19 Pathophysiology Part I: Oligomeric (Soluble) Fibrin Forming Transient Microclots Enhances the Lethality of Covid-19

2021-01-09

Abstract excerpt

We propose that in severely ill patients the SARS-CoV-2 virus expropriates an anomalous variant of clotting. This clotting variant produces a “bloodstream blizzard” of short-chain, soluble, fibrin molecules. If clotting continues, additional polymerization occurs and the molecular chains lengthen. With this lengthening fibrin becomes insoluble and microclots form. These microclots transiently or permanently occlud...

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Literature Corpus work: a3c32f3a-8feb-5d61-8459-b373cf99cb93
DOI: 10.21203/rs.3.rs-142174/v1

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