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Article

Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies

2023-01-20

Abstract excerpt

Monitoring the activity of mice within their home cage is proving to be a powerful tool for revealing subtle and early-onset phenotypes in mouse models. Video tracking, in particular, lends itself to automated machine-learning technologies that have the potential to improve the manual annotations carried out by humans. This type of recording and analysis is particularly powerful in objective phenotyping, monitorin...

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Literature Corpus work
a35c4d79-5d19-5354-a204-4631e645ab0b
DOI
10.1101/2023.01.19.524755
Open publication

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Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studiesDOI 10.1101/2023.01.19.524755
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