Article

Complex pathways to ceftolozane-tazobactam resistance in clinical <i>Pseudomonas aeruginosa</i> isolates: a genomic epidemiology study

2025-05-13

Abstract excerpt

<h4>Objectives</h4> We aimed to conduct a comprehensive genomic analysis of ceftolozane/tazobactam (C/T) resistance mechanisms in Pseudomonas aeruginosa by combining novel institutional data with publicly available sequencing data. <h4>Methods</h4> We analysed 1,682 P. aeruginosa isolates, comprising 339 isolates from Alfred Hospital (Melbourne, Australia) and 1,343 isolates from six public datasets. All isol...

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Literature Corpus work: a35b93cb-3b66-5c78-bd47-97c43a06d467
DOI: 10.1101/2025.05.13.25327501

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