Rising threats of ceftolozane-tazobactam resistance in P. aeruginosa and A. baumannii: Species-, phenotype-, and geography-specific insights from a systematic review and meta-analysis.

doi:10.1016/j.ijmmb.2026.101203

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Rising threats of ceftolozane-tazobactam resistance in P. aeruginosa and A. baumannii: Species-, phenotype-, and geography-specific insights from a systematic review and meta-analysis.

Indian journal of medical microbiology - 1 Jan 2026

Wang Hongda, Qiang Weidong, Fan Guoqiang

Abstract excerpt

BACKGROUND: Ceftolozane-tazobactam (C/T) is increasingly used to treat multidrug-resistant Gram-negative infections, but rising resistance threatens its effectiveness. Understanding global patterns is essential for guiding therapy and stewardship. METHODS: We conducted a systematic review and meta-analysis of studies reporting C/T resistance in Pseudomonas aeruginosa and Acinetobacter baumannii. Pooled resistance...

Read the complete abstract on PubMed

Topics

Tazobactam
Pseudomonas aeruginosa
Third Generation Cephalosporins
Humans
Anti-Bacterial Agents
Acinetobacter baumannii

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cephalosporins

Drug Resistance, Multiple, Bacterial

Phenotype

Microbial Sensitivity Tests

Pseudomonas Infections

Acinetobacter Infections

Geography

Source

Open in PubMed

Identifiers

PMID: 42401360
DOI: 10.1016/j.ijmmb.2026.101203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rising threats of ceftolozane-tazobactam resistance in P. aeruginosa and A. baumannii: Species-, phenotype-, and geography-specific insights from a systematic review and meta-analysis.PMID 42401360Read ↗

Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance MechanismsSemantic proximity Read ↗

Molecular characterization of clinically isolated Pseudomonas aeruginosa with varying resistance to ceftazidime-avibactam and ceftolozane-tazobactam collected as a part of the ATLAS global surveillance program from 2020 to 2021Semantic proximity Read ↗

Molecular mechanisms leading to ceftolozane/tazobactam resistance in clinical isolates of Pseudomonas aeruginosa from five Latin American countriesSemantic proximity Read ↗

Complex pathways to ceftolozane-tazobactam resistance in clinical <i>Pseudomonas aeruginosa</i> isolates: a genomic epidemiology studySemantic proximity Read ↗

Antimicrobial Activity of Ceftazidime-Avibactam, Ceftolozane-Tazobactam and Comparators Tested Against Pseudomonas aeruginosa and Klebsiella pneumoniae Isolates from United States Medical Centers in 2016-2018.Semantic proximity Read ↗

Ceftolozane/Tazobactam Resistance and Mechanisms in Carbapenem-Nonsusceptible Pseudomonas aeruginosaSemantic proximity Read ↗

Portrait of a killer: Uncovering resistance mechanisms and global spread of Acinetobacter baumannii.Semantic proximity Read ↗

Italian nationwide survey on Pseudomonas aeruginosa from invasive infections: activity of ceftolozane/tazobactam and comparators, and molecular epidemiology of carbapenemase producersSemantic proximity Read ↗

Global update on the in vitro activity of tigecycline and comparators against isolates of Acinetobacter baumannii and rates of resistant phenotypes (2016-2018).Semantic proximity Read ↗

Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam inPseudomonas aeruginosaisolates recovered from ICU patients in Spain and Portugal depicted by WGSSemantic proximity Read ↗

Acinetobacter baumannii: an evolving and cunning opponentSemantic proximity Read ↗

Susceptibility of Ceftazidime-avibactam in bloodstream infections caused by multidrug-resistant Enterobacterales and Pseudomonas aeruginosaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.