Article

Subtype-Resolved Pain-Signaling Architectures Reveal Conserved Drug-Target Interaction Networks in DRG Nociceptors

2026-04-15

Abstract excerpt

<h4>ABSTRACT</h4> Pain management has been challenging and a major obstacle lies in the limited translational success between preclinical studies, often based on rodent models and evoked nociception behavioral assays, whose validity is often questioned. The dorsal root ganglia (DRG) contains diverse nociceptor subtypes that serve as the primary afferent pathways for detecting painful stimuli and analgesics often...

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Literature Corpus work: a32ffa61-6e0a-51ab-b6e5-21761b4cf7fa
DOI: 10.64898/2026.04.14.718550

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