Article

Clinical Determinants of Disease Progression in Patients with Beta-sarcoglycan Gene Mutations.

2020-12-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Limb Girdle Muscular Dystrophy 2E (LGMD 2E), recently renamed as autosomal recessive limb-girdle muscular dystrophy-4 (LGMDR4), is characterized by the lack of beta-sarcoglycan, normally expressed in skeletal muscles and cardiomyocytes. We hypothesized that progressive respiratory and left ventricular (LV) failure in LGMDR4 could be associated to the age and int...

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Literature Corpus work: a329299d-ff43-5d2d-9243-6aa01cd5e2cf
DOI: 10.21203/rs.3.rs-127302/v1

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