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Article

LGMDD1 natural history and phenotypic spectrum: Implications for clinical trials.

Annals of clinical and translational neurology - 1 Feb 2023

Findlay Andrew R, Robinson Sarah E, Poelker Stephanie, Seiffert Michelle, Bengoechea Rocio, Weihl Conrad C

Abstract excerpt

OBJECTIVE: To delineate the full phenotypic spectrum and characterize the natural history of limb girdle muscular dystrophy type D1 (LGMDD1). METHODS: We extracted age at clinical events of interest contributing to LGMDD1 disease burden via a systematic literature and chart review. Manual muscle testing and quantitative dynamometry data were used to estimate annualized rates of change. We also conducted a...

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Identifiers

PMID: 36427278
DOI: 10.1002/acn3.51709
PMCID: PMC9930420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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