Article

Host response to cholestyramine can be mediated by the gut microbiota

2020-12-09

Abstract excerpt

The gut microbiome has been implicated as a major factor contributing to metabolic diseases as well as being contributors to the response to drugs used for the treatment of such diseases. In this study, using a diet-induced obesity mouse model, we tested the effect of cholestyramine, a bile acid sequestrant, on the murine gut microbiome and mammalian metabolism. We also explored the hypothesis that some beneficial...

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Identifiers and source

Literature Corpus work: a30b820e-8c53-5c20-8dfa-53558d289211
DOI: 10.1101/2020.12.08.416487

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