Article

Homotypic endoplasmic reticulum membrane tethering is critical for flavivirus replication

2025-11-27

Abstract excerpt

Flaviviruses (genus Orthoflavivirus ) are arthropod-borne viruses which cause approximately 400 million annual global infections in humans. Flavivirus infection requires cellular machinery to facilitate replication and spread. All known flaviviruses replicate in association with the host endoplasmic reticulum (ER), where genome replication is confined within virus-induced ER invaginations called viral replication...

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Literature Corpus work: a23d6da3-4952-545d-8780-4eefb597354d
DOI: 10.1101/2025.11.26.690702

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