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Article

A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer

2015-11-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Sequencing of both healthy and disease singletons yields many novel and low frequency variants of uncertain significance (VUS). Complete gene and genome sequencing by next generation sequencing (NGS) significantly increases the number of VUS detected. While prior studies have emphasized protein coding variants, non-coding sequence variants have also been proven to significan...

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Literature Corpus work
a21c1b26-3ef4-5320-a9f2-4e54c8d3833c
DOI
10.1101/031419
Open publication

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A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancerDOI 10.1101/031419
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