Article

A phase I trial investigating the clinical safety and anti-tumor efficacy of a new generation of oncolytic adenovirus, Ad-TD-nsIL12, in Recurrent Glioblastoma

2023-12-22

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma is one of the most fatal malignancies of the central nervous system, with high mortality and post-treatment recurrence rates. Oncolytic viruses are attractive treatment options for this disease, but must be improved to enhance efficacy and safety. Here we describe a phase I, dose-escalating trial to study the safety of Ad-TD-nsIL12, a novel oncolytic adenovirus expressing a...

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Literature Corpus work: a1e10be8-7ecf-5961-b4c4-95e8b5a6a665
DOI: 10.21203/rs.3.rs-3741744/v1

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A phase I trial investigating the clinical safety and anti-tumor efficacy of a new generation of oncolytic adenovirus, Ad-TD-nsIL12, in Recurrent GlioblastomaDOI 10.21203/rs.3.rs-3741744/v1Read

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