Article

Characterization and functional analysis of a cAMP-dependent protein kinase A catalytic subunit gene (pka1) in Sclerotinia sclerotiorum.

2004-03-01

Abstract excerpt

Increased cAMP levels inhibit sclerotial development and raise oxalate production in Sclerotinia sclerotiorum. These effects were hypothesized to be mediated by protein kinase A (PKA). To test this hypothesis, a pka1 catalytic subunit gene was cloned and disrupted. Southern hybridization confirmed disruption, and northern analysis revealed loss of a wild-type pka1 transcript. Mutant strains were cAMP-responsive, p...

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Literature Corpus work: a1aaafc7-1b5c-5a74-b3a8-0da12d5a99b3
DOI: 10.1016/j.pmpp.2004.07.004

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