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A novel RNA nucleic acid amplification test more accurately distinguishes active <i>Clostridioides difficile</i> infection from colonization

2026-02-06

Abstract excerpt

Clostridioides difficile (C. diff) is a leading cause of hospital-acquired infections with severity ranging from mild diarrhea to fulminant colitis and death. Current antigen tests lack adequate sensitivity and DNA-based nucleic acid amplification tests (DNA-NAATs) exhibit limited specificity for active infection, leading to either underdiagnosis or inappropriate treatment of colonized individuals. Unlike DNA, mRN...

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Literature Corpus work
a18816f3-752d-50de-a2c3-d859c46b4c39
DOI
10.64898/2026.02.05.25342495
Open publication

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A novel RNA nucleic acid amplification test more accurately distinguishes active <i>Clostridioides difficile</i> infection from colonizationDOI 10.64898/2026.02.05.25342495
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