Article

Functional genomic studies of cancer immune evasion using in vitro and in vivo CRISPR/Cas9 genetic screens

2020-01-01

Abstract excerpt

Recent advances in cancer immunology have shed light on the mechanisms of cancer immune evasion. An accumulation of data in recent years has identified several immune checkpoints, whose expression by cancer cells allows them to evade anti-cancer immune responses. The great potential of these findings is highlighted by the recent approval of therapeutic antibodies blocking PD1 and CTLA4, for the treatment of variou...

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Literature Corpus work: a163274c-0644-524e-b7ae-787e016bba6b
DOI: 10.17863/cam.65299

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