Article

Nitrous Oxide Enhances Focused Ultrasound Mediated Delivery of Viral Gene Therapy

2021-07-12

Abstract excerpt

Transcranial Magnetic Resonance Guided Focused Ultrasound (MRgFUS) can be used in conjunction with intravenous microbubbles to open the blood brain barrier (BBB) in discrete brain regions. This method is limited by the microbubble dose, the amount of energy that can be safely delivered across an intact skull, and the inability to target areas of the brain outside of central brain regions. We find that N 2 O admin...

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Literature Corpus work: a136b5a9-906b-515b-9764-6f323d981d3e
DOI: 10.1101/2021.07.11.451978

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