Article

Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection

2024-10-22

Abstract excerpt

Best known for their ability to kill infected or malignant cells, natural killer (NK) cells are also underappreciated regulators of the antibody response to viral infection. In mice, NK cells can kill T follicular helper (Tfh) cells, decreasing somatic hypermutation and vaccine responses. Although human NK cell activation correlates with poor vaccine response, the mechanisms of human NK cell regulation of adaptive...

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Literature Corpus work: a057738d-ee8c-525d-b4c7-79d3c894d8c4
DOI: 10.1101/2024.10.22.619639

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