Article
Disease association with frequented regions of genotype graphs
2020-09-27
Abstract excerpt
Complex diseases, with many associated genetic and environmental factors, are a challenging target for genomic risk assessment. Genome-wide association studies (GWAS) associate disease status with, and compute risk from, individual common variants, which can be problematic for diseases with many interacting or rare variants. In addition, GWAS typically employ a reference genome which is not built from the subjects...
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Identifiers and source
- Literature Corpus work
- a039c036-02c2-5017-9f9c-01761cd7b652
- DOI
- 10.1101/2020.09.25.20201640