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Nocturnal intraocular pressure rise is regulated by norepinephrine via RHOB

2025-03-25

Abstract excerpt

<h4>Summary</h4> Intraocular pressure (IOP), a key factor in glaucoma development, is regulated by aqueous humor (AH) dynamics, with inflow from the ciliary body and outflow through the trabecular meshwork (TM). IOP has a circadian rhythm entrained by sympathetic norepinephrine (NE) from the superior cervical ganglion. Herein, we investigated its underlying regulatory mechanisms in the TM. Through comprehensive g...

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Literature Corpus work
9f5abf06-dc33-51ee-885f-9c0c6ec3a8f7
DOI
10.1101/2025.03.21.644679
Open publication

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