Article
The Immune Response Against Cancer is Modulated by Stromal Cell Fibronectin
2025-05-14
Abstract excerpt
Cancer-associated fibroblasts remain poorly understood, with some of them originating from the bone marrow. We therefore took advantage of the diversity of bone marrow stromal cells to shed light on how fibroblasts modulate cancer growth. In two murine cancer models, adding these fibroblasts to tumor cells resulted in smaller lesions. Suppression was enhanced by pretreatment with fibronectin, while genetic deletio...
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Identifiers and source
- Literature Corpus work
- 9f598f33-603c-58a8-bb72-0d1d65cf974f
- DOI
- 10.1101/2025.05.14.653424