Article

Multi-omics integration in Esophageal Adenocarcinoma reveals therapeutic targets and EAC-specific regulation of protein abundances

2022-11-29

Abstract excerpt

<h4>Background</h4> Efforts to address the poor prognosis associated with esophageal adenocarcinoma (EAC) have been hampered by a lack of biomarkers to identify early disease and therapeutic targets. Despite extensive efforts to understand the somatic mutations associated with EAC over the past decade, a gap remains in understanding how the atlas of genomic aberrations in this cancer impacts the proteome. Differen...

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Literature Corpus work: 9f2ee9a2-3414-5dd9-aae0-28deee0950ef
DOI: 10.1101/2022.11.24.22281691

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