Article

Uncarboxylated Osteocalcin Inhibits De Novo Lipogenesis and Promotes Fatty Acid Oxidation via SIRT1 to Alleviate Hepatocyte Lipid Accumulation

2024-02-02

Abstract excerpt

<title>Abstract</title><p>Background Non-alcoholic fatty liver disease (NAFLD) is a disease characterized by the hepatic lipids accumulation resulting from genetic susceptibility and metabolic dysfunction. Uncarboxylated osteocalcin (GluOC) is a protein that is synthesized by osteoblasts which performs a vital function in the management of energy balance. Previous studies have shown that GluOC is beneficial for li...

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Literature Corpus work: 9f0e8d7d-072c-505d-8126-90556c306f50
DOI: 10.21203/rs.3.rs-3856420/v1

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