Improving bioinformatics prediction of microRNA targets by ranks aggregation

Abstract excerpt

microRNAs are non-coding RNAs which down-regulate a large number of target mRNAs and modulate cell activity. Despite continued progress, bioinformatics prediction of microRNA targets remains a challenge since available softwares still suffer from a lack of accuracy and sensitivity. Moreover, these tools show fairly inconsistent results from one another. Thus, in an attempt to circumvent these difficulties, we aggr...

Topics

Open a Topic to create a Post that cites this publication.

• Artificial Intelligence
• Gene Expression
• MicroRNAs
• Oligonucleotide Array Sequence Analysis
• Polymorphism, Single Nucleotide
• Real-Time Polymerase Chain Reaction
• Software
• Support Vector Machine

Identifiers and source

Literature Corpus work

9eea662b-cfc8-5ce3-8457-0057c5f6023e

DOI

10.1101/224915