Article

Clinically-relevant altered antibiotic responses and mechanisms of β-lactam sensitization of MRSA in cystic fibrosis artificial sputum

2026-03-31

Abstract excerpt

Staphylococcus aureus is the most common bacterial pathogen affecting pediatric patients with Cystic fibrosis (CF), a genetic disorder that causes thick mucus buildup in the lungs, providing a scaffold for chronic infections. Antibiotic treatment is typically guided by standard in vitro antimicrobial susceptibility testing (AST) in Mueller-Hinton broth (MHB), which does not represent the infection site in CF lung...

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Literature Corpus work: 9ee5e72b-bffc-5fe4-aa75-b80542b5bd26
DOI: 10.64898/2026.03.30.715424

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