Influence of the lung microbiome on antibiotic susceptibility of cystic fibrosis pathogens

Abstract excerpt

The lungs of patients with cystic fibrosis (CF) are colonised by a microbial community comprised of pathogenic species, such asPseudomonas aeruginosaandStaphylococcus aureus, and microorganisms that are typically not associated with worse clinical outcomes (considered as commensals). Antibiotics directed at CF pathogens are often not effective and a discrepancy is observed between activity of these agentsin...

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