Article

K-means Based Unsupervised Feature Selection to Prioritize Biomarkers of Different Disease Clinical Phases

2020-04-23

Abstract excerpt

Huntington’s disease is caused by a single gene mutation, which is potentially a good model for development of biomarkers corresponding to different disease phase and clinical phenotypes. Hypothesis-driven and omics discovery approaches have not yet identified effective candidate biomarkers in HD. So, it is urgent to develop engagement and disease-phase specific biomarkers. The advanced sequencing technology makes...

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Literature Corpus work: 9eb14506-7a02-533d-8819-53cebb59f8ae
DOI: 10.1101/2020.04.21.052704

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