Article

PathQC: Determining Molecular and Physical Integrity of Tissues from Histopathological Slides

2025-10-01

Abstract excerpt

Quantifying tissue molecular and physical integrity is essential for biobank development. However, current assessment methods either involve destructive testing that depletes valuable biospecimens or rely on manual evaluations, which are not scalable and lead to interindividual variation. To overcome these challenges, we present PathQC, a deep learning framework that directly predicts the tissue RNA Integrity Numb...

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Literature Corpus work: 9e46f2a9-3573-5112-951e-54ce46008e16
DOI: 10.1101/2025.09.29.679347

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