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Overview and Historical Perspectives

21 Nov 2014

Abstract excerpt

In this overview, we describe the history of Shiga toxin (Stx)-producing Escherichia coli (STEC) in two phases. In phase one, between 1977 and 2011, we learned that E. coli could produce Shiga toxin and cause both hemorrhagic colitis and the hemolytic-uremic syndrome in humans and that the prototype STEC-E. coli O157:H7-adheres to and effaces intestinal epithelial cells by a mechanism similar to that of...

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PMID: 25590020
DOI: 10.1128/microbiolspec.ehec-0028-2014

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