Article

Ghrelin-Reactive Autoantibodies are elevated in Children with Prader-Willi Syndrome

2016-12-16

Abstract excerpt

Prader-Willi Syndrome (PWS) is a complex genetic disorder characterized by developmental and growth abnormalities, insatiable appetite, and excessive eating (hyperphagia). The underlying cause of hyperphagia in PWS is currently unknown, however, elevated levels of the peptide hormone ghrelin is believed to contribute. Recently, ghrelin-reactive autoantibodies (isotype IgG) were identified in non-genetic obesity. T...

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Literature Corpus work: 9dd5e6f8-ee91-50e3-ae69-9cef634ec96a
DOI: 10.1101/093930

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