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Article

Elevated ratio of acylated to unacylated ghrelin in children and young adults with Prader-Willi syndrome.

Endocrine - 1 Dec 2015

Kuppens R J, Diène G, Bakker N E, Molinas C, Faye S, Nicolino M, Bernoux D, Delhanty P J D, van der Lely A J, Allas S, Julien M, Delale T, Tauber M, Hokken-Koelega A C S

Abstract excerpt

Prader-Willi syndrome (PWS) is characterized by a switch from failure to thrive to excessive weight gain and hyperphagia in early childhood. Hyperghrelinemia may be involved in the underlying mechanisms of the switch. The purpose of this study is to evaluate acylated ghrelin (AG) and unacylated ghrelin (UAG) levels in PWS and investigate their associations with hyperphagia. This is a cross-sectional clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25989955
DOI: 10.1007/s12020-015-0614-x
PMCID: PMC4662713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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