Copper Chaperone for Superoxide Dismutase Expression is Down-Regulated and Correlated with More Malignant Tumoral Features and Poor Prognosis in Human Hepatocellular Carcinoma

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Up-regulated expression of copper chaperone for superoxide dismutase (CCS) is identified in a multitude of tumors and is closely related to more malignant tumoral biological behaviors. However, little is known about the role of CCS in hepatocellular carcinoma (HCC). This study aims to explore the expression pattern and the significance of CCS in human HCC.<bold>...

Topics

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• Cancer Mechanisms and Therapy
• Carcinoma, Hepatocellular
• Cytokine Signaling Pathways and Interactions
• Ferroptosis and cancer prognosis
• Heterografts
• Liver Neoplasms
• MAP Kinase Signaling System
• Mice, Inbred BALB C

Identifiers and source

Literature Corpus work

9d241f81-7753-5c6f-aeb7-456a6f83512a

DOI

10.21203/rs.3.rs-100249/v2