Article

Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications

2020-06-27

Abstract excerpt

Testicular microcalcifications consist of hydroxyapatite and have been associated with an increased risk of testicular germ cell tumors (TGCTs) but are also found in benign cases such as loss-of-function variants in the phosphate-transporter SLC34A2 . Here, we show that fibroblast growth factor 23 (FGF23), a regulator of phosphate homeostasis, is expressed in testicular germ cell neoplasia in situ (GCNIS), embry...

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Literature Corpus work: 9cc3ca21-db62-54e8-9cb0-a9018c8fecf3
DOI: 10.1101/2020.06.25.171355

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