Article

Estradiol modulates gut microbiota in female <i>ob/ob</i> mice fed a high fat diet

2019-04-18

Abstract excerpt

Estrogens protect against diet-induced obesity in women and female rodents. In support of these anorectic effects, lack of estrogens in postmenopausal women is associated with weight gain, increasing their risk for cardiovascular diseases and cancer. Estrogens act with leptin, a satiety hormone encoded by the ob gene, to regulate energy homeostasis in females. Leptin-deficient mice ( ob/ob ) exhibit morbid obesi...

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Literature Corpus work: 9c9b51ee-4d5b-596a-b801-e4ad57b6626c
DOI: 10.1101/612283

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