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Evaluation of the Gut Microbiome and Sex Hormones in Postmenopausal Women with Newly Diagnosed Hormone Receptor-Positive Breast Cancer Versus Healthy Women: A Prospective Case-Control Study

2022-03-29

Abstract excerpt

<title>Abstract</title> <p>Purpose The functional composition and diversity of the gut microbiome (estrobolome) may affect breast cancer risk by modulation of systemic sex hormones. Gut bacteria with β-glucuronidase enzymatic activity may deconjugate estrogens, leading to increased estrogen reabsorption into the circulation thereby increasing breast cancer risk. We investigated the relationship between the gut b...

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Literature Corpus work: 06e3b57f-a9e5-5a13-b3ed-efc588b1e989
DOI: 10.21203/rs.3.rs-1447334/v1

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