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Mycobacterium tuberculosis whole genome sequence data support repurposing antileprosy antibiotic as antituberculosis

2020-08-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> We implanted WGS as the routine method to profile the antibiotic susceptibility of M. tuberculosis isolates focusing on in silico resistance to antileprosy drugs that we recently proposed to reposition for the treatment of pulmonary tuberculosis. <h4>Methods</h4> We prospectively performed WGS of 112 M. tuberculosis isolates recovered from respiratory tract samples of 106 pati...

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Literature Corpus work
9c5de4a6-dbc9-5633-ba8e-2bfb85c29378
DOI
10.1101/2020.08.15.20175570
Open publication

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Mycobacterium tuberculosis whole genome sequence data support repurposing antileprosy antibiotic as antituberculosisDOI 10.1101/2020.08.15.20175570
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