Article

Comparative Analysis of common alignment tools for single cell RNA sequencing

2021-02-16

Abstract excerpt

With the rise of single cell RNA sequencing new bioinformatic tools became available to handle specific demands, such as quantifying unique molecular identifiers and correcting cell barcodes. Here, we analysed several datasets with the most common alignment tools for scRNA-seq data. We evaluated differences in the whitelisting, gene quantification, overall performance and potential variations in clustering or dete...

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Literature Corpus work: 9c1e6959-8299-59ee-b794-7fcf160b0527
DOI: 10.1101/2021.02.15.430948

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