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When does accounting for gene-environment interactions improve complex trait prediction? A case study with <i>Drosophila</i> lifespan

2025-07-17

Abstract excerpt

Gene-environment interactions (G × E) have been shown to explain a non-negligible proportion of variance for a plethora of complex traits in different species, including livestock, plants, and humans. While several studies have shown that including G × E can improve prediction accuracy in agricultural species, no increase in accuracy has been observed in human studies. In this work, we sought to investigate the re...

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Literature Corpus work
9bf8103b-1901-5448-a78e-5f42caf2208f
DOI
10.1101/2025.07.12.664531
Open publication

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When does accounting for gene-environment interactions improve complex trait prediction? A case study with <i>Drosophila</i> lifespanDOI 10.1101/2025.07.12.664531
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