Article

APLP2 as a Molecular Link Between Immune Regulation and Bone Metabolism in Hepatocellular Carcinoma: Evidence from scRNA-Seq and Functional Validation

2025-12-11

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<title>Abstract</title> <p> <bold>Background and Aims:</bold> Hepatocellular carcinoma (HCC) remains a significant health concern worldwide, characterized by elevated mortality rates that are often associated with diagnoses occurring in advanced stages and the restricted efficacy of treatment options currently available. Immune checkpoint inhibitors (ICIs) demonstrate promise in treating HCC; nonetheless, chall...

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Literature Corpus work: 9bb81960-dbe4-56bd-8636-8de1c508c5ba
DOI: 10.21203/rs.3.rs-7785516/v1

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