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Influenza A virus surface proteins are organized to help penetrate host mucus

2019-01-04

Abstract excerpt

Influenza A virus (IAV) enters cells by binding to sialic acid on the cell surface. To accomplish this while avoiding immobilization by sialic acid in host mucus, viruses rely on a balance between the receptor-binding protein hemagglutinin (HA) and the receptor-cleaving protein neuraminidase (NA). Although genetic aspects of this balance are well-characterized, little is known about how the spatial organization of...

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Literature Corpus work
9ba34563-6a60-5067-b747-392c730f33bd
DOI
10.1101/512467
Open publication

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Influenza A virus surface proteins are organized to help penetrate host mucusDOI 10.1101/512467
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