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Article

Alveolar MMP28 is Associated With Clinical Outcomes and Measures of Lung Injury in Acute Respiratory Distress Syndrome

2020-01-08

Abstract excerpt

<h4>Background: </h4> Excessive inflammation leading to increased alveolar-capillary barrier permeability remains the pathogenic model for acute respiratory distress syndrome (ARDS). Alveolar macrophage (AM) polarization has been shown to modify the activity of various matrix metalloproteinases (MMPs) that have downstream effects on key ARDS cytokines/chemokines, however the relationship between AMs, MMP28 (the ne...

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Literature Corpus work
9af5ce98-d17c-543c-ba5a-13d06f75a3cb
DOI
10.21203/rs.2.20294/v1
Open publication

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