Article
The intersection of capsule gene expression, hypermucoviscosity and hypervirulence in Klebsiella pneumoniae.
Current opinion in microbiology - 1 Apr 2020
Walker Kimberly A, Miller Virginia L
Abstract excerpt
For ∼30 years, two distinct groups of clinical isolates of Klebsiella pneumoniae have been recognized. Classical strains (cKp) are typically isolated from patients with some degree of immunocompromise and are not virulent in mouse models of infection whereas hypervirulent strains (hvKp) are associated with community acquired invasive infections and are highly virulent in mouse models of infection. Hyperproduction...
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