Article

Pan-Cancer Drug Response Prediction Using Integrative Principal Component Regression

2023-10-05

Abstract excerpt

The pursuit of precision oncology heavily relies on large-scale genomic and pharmacological data garnered from preclinical cancer model systems such as cell lines. While cell lines are instrumental in understanding the interplay between genomic programs and drug response, it well-established that they are not fully representative of patient tumors. Development of integrative methods that can systematically assess...

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Literature Corpus work: 9a21c6ae-3496-59d6-aac0-963e39b2946c
DOI: 10.1101/2023.10.03.560366

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