Article

Biallelic NEXN variants and fetal onset dilated cardiomyopathy: two independent case reports and revision of literature.

2023-08-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Dilated cardiomyopathy (DCM) is etiologically heterogeneous. With the rapid evolution in laboratory investigations, genetic background is increasingly determined including many genes with variable penetrance and expressivity. Biallelic <italic>NEXN</italic> variants are rare in humans and associated with poor prognosis: fetal and perinatal death or severe DCMs in...

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Literature Corpus work: 999911cc-81c3-5763-bbfc-adbce00e3fc9
DOI: 10.21203/rs.3.rs-3230381/v1

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