Article

Molecular Signature of Peri-Implantitis: An AI-Driven Transcriptomic Analysis Reveals a Foreign-Body Inflammatory Phenotype; A Pilot Study

2025-11-18

Abstract excerpt

Peri-implantitis (PI) is a highly destructive inflammatory disease characterized by progressive bone loss surrounding dental implants. Although it shares clinical features with chronic periodontitis (CP), its aggressive and often refractory nature suggests a distinct pathophysiology. This study employs an AI-driven transcriptomic approach using publicly available human gingival gene expression data (GEO accession:...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 729f2528-f878-5a51-bf0f-eb21a5fb3252
DOI: 10.20944/preprints202511.1347.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Molecular Signature of Peri-Implantitis: An AI-Driven Transcriptomic Analysis Reveals a Foreign-Body Inflammatory Phenotype; A Pilot StudyDOI 10.20944/preprints202511.1347.v1Read

Deciphering Periodontitis: Host Mechanisms, Predictive Biomarkers, and Systemic Drivers for Precision PreventionSemantic proximity Read

Single-Cell Transcriptome Atlas of the Canine Peri-implantitis Reveals stromal–immune cells interactionSemantic proximity Read

Single-cell transcriptomics reveal micro-environment alterations in canine peri-implantitisSemantic proximity Read

Interplay of Systemic Diseases and Genetic Factors in Peri-Implantitis: Integrative Transcriptomic and Clinical Evidence from Patients with Diabetes, Hypertension, and OsteoporosisSemantic proximity Read

Integrative analysis of ferroptosis-related genes and immune infiltration in peri-implantitisSemantic proximity Read

A Personalized, Biomarker-Based Risk Assessment Model for Peri-Implantitis: Integration of Clinical, Molecular, and Microbial PredictorsSemantic proximity Read

The underlying molecular mechanisms and biomarkers between periodontitis and COVID- 19Semantic proximity Read

Single-cell RNA sequencing reveals rebalancing of immunological response in patients with periodontitis after non-surgical periodontal therapySemantic proximity Read

Peri‐Implantitis versus Periodontitis: Functional Differences Indicated by Transcriptome ProfilingSemantic proximity Read

Identification of Differentially Expressed Genes Related to UFMylation Modifications in Periodontitis: Integrated Insights from Transcriptomics and Clinical ExperimentsSemantic proximity Read

CD38⁺ Endothelial Remodeling Defines Spatially Diverse Vasculopathy Programs in Rapidly Advancing Oral InflammationSemantic proximity Read

Development of an immunogenomic landscape for the competing endogenous RNAs network of peri-implantitisSemantic proximity Read