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Acquired RhD positivity loss mediated by promoter hypermethylation is associated with adverse outcome in Myelodysplastic Syndrome: a case report and literature review

2025-12-12

Abstract excerpt

<title>Abstract</title> <p> Background The RhD antigen is a critical immunogenic protein on red blood cells. Acquired loss of RhD expression in individuals with a previous positive phenotype is a rare event, most often reported in hematological malignancies. Case presentation A 58-year-old woman with intermediate-risk myelodysplastic syndrome (MDS) was admitted with fever. Routine blood typing revealed a discrep...

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Literature Corpus work
98e4abd6-224d-5a54-8766-8b1cd774bb7a
DOI
10.21203/rs.3.rs-8004178/v1
Open publication

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