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Guanylate binding protein 2b contributes to M1 macrophage polarization during Mycobacterium bovis infection

2022-05-16

Abstract excerpt

Accumulating evidence has demonstrated that the macrophage phenotype switch from M0 to M1 is critical in the clearance of intracellular mycobacteria during Mycobacterium bovis infection. In this study, the entire gene expression profiles of M1 bone marrow-derived macrophages (BMDMs) induced by interferon-gamma and lipopolysaccharide, M2 BMDMs induced by interleukin (IL) - 4 and IL-13, M0 BMDMs, and M0 BMDMs after...

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Literature Corpus work
9877163b-8aa8-5821-a4f8-f9331c6d1b3a
DOI
10.21203/rs.3.rs-1631961/v1
Open publication

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Guanylate binding protein 2b contributes to M1 macrophage polarization during Mycobacterium bovis infectionDOI 10.21203/rs.3.rs-1631961/v1
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