Article

Cluster Analysis Identified Clinically Relevant Metabolic Syndrome Endophenotypes

2022-11-05

Abstract excerpt

<h4>Aims/hypothesis</h4> Metabolic syndrome (MetS) is a collection of cardiovascular risk factors; however, the high prevalence and heterogeneity impede proper and effective clinical management of MetS. In order for precision medicine to work for MetS, we aimed to identify clinically relevant MetS sub-phenotypes. <h4>Methods</h4> We conducted cluster analysis on individuals from UK Biobank based on MetS criteria t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 98413eb6-2874-5e11-8dca-6640ad1feaea
DOI: 10.1101/2022.11.04.22281926

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cluster Analysis Identified Clinically Relevant Metabolic Syndrome EndophenotypesDOI 10.1101/2022.11.04.22281926Read

Unsupervised clustering identified clinically relevant metabolic syndrome endotypes in UK and Taiwan BiobanksSemantic proximity Read

Data-driven cluster analysis identifies distinct types of cardiovascular-kidney-metabolic syndromeSemantic proximity Read

Genetics of metabolic syndrome: is there a role for phenomics?Semantic proximity Read

Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome.Semantic proximity Read

Metabolic syndrome: genetic insights into disease pathogenesis.Semantic proximity Read

Unraveling phenotypic variance in metabolic syndrome through multi-omics.Semantic proximity Read

Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. BiobankSemantic proximity Read

Clustering beyond the binary: Stable machine-learning phenotypes of metabolic syndrome.Semantic proximity Read

Metabolic syndrome: from epidemiology to systems biology.Semantic proximity Read

Does the metabolic syndrome exist? The identification of cardio-metabolic profiles in a South Asian population studySemantic proximity Read

[Genetic Susceptibility to Metabolic Syndrome: A Comparative Overview of the Mexican Population in a Global Context].Semantic proximity Read

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.Semantic proximity Read